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Navigating CBG and CBD: Understanding Benefits, Combinations, and Risks
Aug
Understanding CBG: The Mother of All Cannabinoids
Cannabigerol (CBG) is gaining attention in the world of natural health and wellness. Often called the “mother of all cannabinoids,” CBG plays a unique role in the cannabis plant and offers potential benefits for human health. Let’s explore what CBG is, its benefits, how it interacts with CBD, and who should exercise caution when using it.
What is CBG?
Definition and Origin of CBG
(CBG) is a non-psychoactive cannabinoid found in cannabis plants. It was first discovered in 1964 by Israeli researchers Yehiel Gaoni and Raphael Mechoulam, the same scientists who isolated THC.
Production in Cannabis Plants
CBG is produced in the early stages of the plant’s growth cycle. As the plant matures, enzymes convert CBGA (the acidic form of CBG) into other cannabinoids like THC and CBD. This is why CBG is often called the “mother” or “stem cell” of cannabinoids.
Comparison to Other Cannabinoids
Unlike THC, CBG does not produce intoxicating effects. It’s more similar to CBD in this regard. However, CBG interacts with the endocannabinoid system differently than both THC and CBD, potentially offering unique benefits.
What are the Benefits?
Potential Therapeutic Uses
Research into CBG is still in its early stages, but preliminary studies suggest it may have several potential therapeutic applications:
- Anti-inflammatory properties
- Neuroprotective effects
- Antibacterial action
- Appetite stimulation
- Potential to fight cancer cells
Current Research Findings
While more research is needed, studies have shown promising results for CBG in various areas:
- A 2015 study found CBG might protect neurons in mice with Huntington’s disease.
- A 2020 study suggested CBG could be effective against antibiotic-resistant bacteria.
- Research from 2014 indicated CBG might inhibit the growth of colorectal cancer cells.
Specific Health Conditions That May Benefit
Based on current research, CBG might be beneficial for the below, but research on the topic is ongoing and again, should be consulted and then discussed with your doctor if you plan on adding CBG to your regimen.
- Inflammatory bowel diseases
- Glaucoma
- Bladder dysfunctions
- Bacterial infections
- Loss of appetite
CBG and CBD: A Powerful Combination?
Potential Synergistic Effects
Using CBG and CBD together may enhance their individual benefits due to the “entourage effect.” This theory suggests that cannabinoids work better together than in isolation.
The Entourage Effect Explained
The entourage effect posits that the various compounds in cannabis work synergistically, potentially enhancing their therapeutic effects when used together.
Addressing Misconceptions About Getting “High”
It’s important to note that neither CBG nor CBD will get you “high” or “stoned.” These cannabinoids do not have the psychoactive properties associated with THC. So if you’re looking for a more elevated plateau of consciousness, then CBG isn’t going to get you there. But THC will…
Differences in Psychoactive Effects
While THC binds directly to CB1 receptors in the brain, causing the “high” sensation, CBG and CBD do not. They interact with the endocannabinoid system in different ways, which is why they don’t produce intoxicating effects.
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Who Should Avoid CBG?
While CBG shows promise, certain groups should exercise caution or avoid its use:
People Subject to Drug Testing: While CBG itself isn’t typically tested for, some CBG products may contain trace amounts of THC, which could potentially trigger a positive drug test.
Pregnant and Breastfeeding Women: Due to limited research on CBG’s effects during pregnancy and lactation, it’s best to avoid use.
People with Specific Medical Conditions: Those with liver disease or other conditions affecting drug metabolism should consult a healthcare provider before using CBG.
Individuals on Certain Medications: CBG may interact with certain medications, particularly those metabolized by the liver. As we’ve stressed, the research on CBG is ongoing, so always consult your doctor if you’re taking any medications.
Those with Cannabis Sensitivity: Some people may be sensitive to cannabis compounds, including CBG.
Ultimately, CBG represents an exciting frontier in cannabinoid research. While it shows promise for various health applications, it’s crucial to approach its use responsibly and consult with a healthcare professional, especially if you have any underlying health conditions or concerns. As noted, CBG’s non-intoxicating nature has promise for treating a range of health conditions, but human research is still in its very early stages. CBG’s safety profile, in particular, its long-term risks with chronic usage, is an unknown and requires more investigation. Certain segments like pregnant women, minors, and people with allergies or medical conditions may face increased risks from CBG that outweigh potential benefits currently. For anyone able to use CBG, do so under medical supervision, and start off with low doses.
CBG and CBD Resources
- Reputable scientific journals and databases:
- PubMed Central (PMC): https://www.ncbi.nlm.nih.gov/pmc/
- Journal of Cannabis Research: https://jcannabisresearch.biomedcentral.com/
- Government health websites:
- National Center for Complementary and Integrative Health (NCCIH): https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
- National Institute on Drug Abuse (NIDA): https://nida.nih.gov/research-topics/marijuana
- Trusted cannabis research organizations:
- International Cannabinoid Research Society (ICRS): https://icrs.co/
- The International Association for Cannabinoid Medicines (IACM): https://www.cannabis-med.org/
These resources provide reliable, science-based information on cannabinoids, including CBG. They offer a mix of peer-reviewed research, government health guidelines, and expert insights from organizations dedicated to cannabis research. Remember to always cross-reference information and consult with healthcare professionals for personalized advice.
More Resources
Want more reading? Check out our Virtual AI Education Hub, with AI video 101’s, a dictionary, FAQ’s and other sources for you, the true end-user. Ensure that you’re purchasing safe, effective, and high-quality CBD products for your health and wellness needs.
Note: The hemp/cannabis industry has been an extremely busy one lately. We encourage anyone interested in seeing how it develops (and literally, how history is being made), to visit the NCIA site: https://thecannabisindustry.org/.
